Instruments to measure skills and knowledge of physicians and medical students in palliative care: A systematic review of psychometric properties.

PURPOSE: Palliative care is constantly increasing around the world. The knowledge and skills of future physicians in this area are crucial. This study evaluates the psychometric properties of knowledge and skills questionnaires used in palliative care, validated by physicians or medical students based on the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology. METHODS: A systematic review was carried out in Cosmin Databases, Cochrane Library, PsycINFO, SciELO, Cinahl, and Medline up to September 2020 (updated June 2021), based on the COSMIN methodology and PRISMA recommendations. The psychometric properties of each included questionnaire were identified. Methodological quality, quality of results, and quality of evidence were evaluated. RESULTS: The search strategy yielded 12 questionnaires assessing the knowledge and skills of physicians or medical students. The Palliative Care Knowledge Questionnaire for PEACE (PEACE-Q) and Palliative Care Knowledge Test (PCKT) were the instruments with the highest scores for methodological quality, quality of results, and quality of evidence-based on the COSMIN methodology. CONCLUSIONS: PEACE-Q and PCKT should be the preferred choice to assess palliative care knowledge and skills in physicians. In-depth studies following COSMIN validation criteria are recommended to improve the psychometric properties and cross-cultural validation of the questionnaires.

Palliative care knowledge test for nurses and physicians: validation and cross-cultural adaptation.

BACKGROUND: Palliative care knowledge is essential in primary healthcare due to the increasing number of patients who require attention in the final stage of their life. Health professionals (physicians and nurses) need to acquire specific knowledge and abilities to provide high-quality palliative care. The development of education programmes in palliative care is necessary. The Palliative Care Knowledge Test (PCKT) is a questionnaire that evaluates the basic knowledge about palliative care, but it has not been adapted into Spanish, and its effectiveness and utility for Spanish culture have not been analysed. OBJECTIVE: The aim of this study was to report the translation into Spanish and a psychometric analysis of the PCKT. METHODS: The questionnaire survey was validated with a group of 561 physicians and nurses. The PCKT Spanish Version (PCKT-SV) was obtained from a process, including translation, back translation and revision by experts and a pilot study. The content validity and reliability of the questionnaire were analysed. RESULTS: The results showed internal consistency and reliability indexes similar to those obtained by the original version of PCKT. CONCLUSION: The PCKT-SV is a useful instrument for measuring Spanish-speaking physician and nurse knowledge of palliative care, and it is suitable to evaluate the effectiveness of training activities in palliative care.

Physicians' and Nurses' Knowledge in Palliative Care: Multidimensional Regression Models.

The increase in life expectancy has led to a growth in the number of people in need of palliative care. Health professionals must possess appropriate knowledge and skills. This study aimed to assess knowledge in palliative care through the Palliative Care Knowledge Test Spanish Version (PCKT-SV)®. A cross-sectional analytical study was conducted in 40 primary care health services. A total of 600 PCKT-SV questionnaires were distributed among health professionals; 561 of them (226 nurses and 335 physicians) were properly filled up. Sociodemographic information, education, and work experience were also recorded. A total of 34.41% of the nurses and 67.40% of the physicians showed good or excellent knowledge of palliative care. Physicians' scores for pain, dyspnea, and psychiatric disorders were higher than those of the nurses. Nurses scored significantly better in philosophy. Professionals with continuous training in palliative care showed a higher level of knowledge. Age and work experience of physicians and undergraduate training in nurses had significant weight in knowledge. Developing continuous training and enhancing undergraduate training in palliative care will lead to improved patient care at the end of life.

Palliative care undergraduate education: Do medical and nursing students need more skills in ethical and legal issues?

This study aimed to analyze the schools that teach ethical and legal aspects within the subject of palliative care in the degrees of medicine and nursing in Spain. MATERIAL AND METHODS: Descriptive Analysis of the palliative care subject and their ethical and legal curricular competencies in the Spanish Nursing and Physicians undergraduate. The training received in legal ethical aspects related to palliative care was compared with the criteria established by the European Association for Palliative Care (EAPC). DATA SOURCES: The National Conference of Nursing Deans, The National Conference of Spanish Medical Faculty Deans and The Ministry of Science, Innovation, and Universities databases were searched. RESULTS: Twenty-one universities have an undergraduate in medicine with palliative care in their curricular training explicitly. The degree in nursing is present in fifty-six universities, palliative care is present in 62.5% of the cases. The degrees of nursing and medicine receive approximately the same level of training in ethical and legal aspects of palliative care. CONCLUSION: The specific training received in ethical and legal issues of palliative care must be improved in medical and nursing to meet the EAPC levels.

Riesgo de enfermedad neumocócica en pacientes ancianos con y sin vacunación previa / Risk of pneumococcal disease in elderly patients with and without previous vaccination

Objetivos: Conocer la cobertura vacunal antineumocócica en pacientes ≥ 65 años, así como el riesgo de enfermedad neumocócica según hayan o no recibido dicha vacunación. Diseño: Estudio transversal, seguido de cohorte histórica. Emplazamiento: Ámbito urbano. Participantes: Se seleccionaron por muestreo sistemático 2.805 personas ≥ 65 años de la ciudad de Albacete. Mediciones principales: Variable dependiente: diagnóstico de enfermedad neumocócica y fecha. Variables independientes: edad, sexo, enfermedades crónicas, medicación, vacunación antineumocócica y fecha. Se revisaron las historias clínicas informatizadas, de 1-1-2009 a octubre-diciembre de 2015. Se ha realizado un análisis descriptivo, se ha calculado el riesgo relativo de aparición de enfermedad neumocócica según la vacunación y se ha realizado un análisis de supervivencia con el programa estadístico SPSS 17.0. Resultados: La mediana de edad era de 71 años; el 57,2% eran mujeres. Recibieron vacuna polisacárida el 46,0% (IC 95% 44,1-47,8). Solo 10 recibieron la conjugada. Fueron diagnosticadas de enfermedad neumocócica invasiva 22 personas, y de no invasiva, 153. El riesgo relativo de enfermedad neumocócica en vacunados frente a no vacunados, respectivamente para invasiva y no invasiva, era 1,59 (IC 95% 0,69-3,68) y 1,84 (IC 95% 1,33-2,54). Por regresión de Cox se demostró un mayor riesgo de enfermedad no invasiva para EPOC (1,95; IC 95% 1,32-2,89), tabaquismo (1,87; IC 95% 1,28-2,73), corticoterapia (1,73; IC 95% 1,08-2,79), vacunación polisacárida (141,41; IC 95% 5,92-3.378,49) y edad (1,11; IC 95% 1,08-1,14), con interacción entre estas 2 (0,94; IC 95% 0,91-0,98). Conclusiones: Existe un mayor riesgo de presentar enfermedad neumocócica en pacientes ≥ 65 años vacunados con la polisacárida, si bien habría que considerar un efecto protector en los vacunados de mayor edad

Objectives: To know the pneumococcal vaccination coverage in patients ≥ 65 years old, as well as the risk of pneumococcal disease according to whether or not they received such vaccination. Design: Cross-sectional study, followed by historical cohort. Location: Urban area. Participants: By systematic sampling, 2,805 people ≥ 65 years from the city of Albacete were selected. Main measurements: Dependent variable: diagnosis of pneumococcal disease and date. Independent variables: age, sex, chronic pathologies, medication, pneumococcal vaccination and date. The computerized medical records were reviewed, from 1-1-2009 to October-December 2015. A descriptive analysis was carried out, the relative risk of the onset of pneumococcal disease according to vaccination has been calculated, and survival analysis has been carried out, with the statistical program SPSS 17.0. Results: Median age 71 years; 57.2% were women; 46% received polysaccharide vaccine (95% CI 44.1-47.8). Only 10 people received conjugated vaccine. Twenty-two people were diagnosed with invasive pneumococcal disease and 153 non-invasive. The relative risk of pneumococcal disease in vaccinated versus unvaccinated, respectively for invasive and non-invasive, was 1.59 (95% CI 0.69-3.68) and 1.84 (95% CI 1.33-2.54). Cox regression showed a higher risk of non-invasive disease for COPD (1.95; 95% CI 1.32-2.89), smoking (1.87; 95% CI 1.28-2.73), corticoid-therapy (1.73; 95% CI 1.08-2.79), polysaccharide vaccination (141.41; 95% CI 5.92-3,378.49) and age (1.11; 95% CI 1.08-1.14), with interaction between these 2 (0.94, 95% CI 0.91-0.98). Conclusions: There is an increased risk of pneumococcal disease in patients ≥ 65 years vaccinated with polysaccharide, although with a protective effect in vaccinated older

Adherencia a la vacunación antigripal de personas mayores tras participar en talleres específicos / Adherence to influenza vaccination among elderly people after participating in specific workshops

Objetivo: Conocer el seguimiento de la vacunación antigripal por ancianos que habían participado en talleres específicos. Diseño: Estudio cuasiexperimental. Emplazamiento: Atención Primaria. Participantes: Se incluyeron 76 personas participantes en talleres sobre gripe y, como controles, 116 que no lo habían hecho. Mediciones Principales: Se comparó el porcentaje de vacunación entre los años 2009 y 2013, según el registro en la historia clínica informatizada. Por análisis de supervivencia se determinó el tiempo de adherencia, considerando "falta de cumplimiento" la primera vez sin vacunar. Resultados: La proporción de vacunados era más alta en los participantes en los talleres: 68,6 % (IC 95 %: 54,9-82,3) vs 61,2 % (IC 95 %: 51,9-70,5) en los que no habían participado, pero sin diferencias estadísticamente significativas (NS). La vacunación se interrumpió en el 45,1 % (IC 95 %: 30,5-59,7) y 42,2 % (IC 95 %: 32,8-51,7), respectivamente, con un cumplimiento medio de 2 años en ambos grupos (NS). Se encontraron diferencias significativas entre ambos grupos para quienes no habiéndose vacunado el año anterior a su inclusión en el estudio, sí lo hacían al año siguiente: 14,9 % vs 5 %, respectivamente para participantes y no participantes en talleres (p < 0,05). Conclusiones: Aunque la asistencia de personas mayores a talleres específicos sobre gripe puede estimular la vacunación inicialmente, no existe una mejora significativa a largo plazo

Objective: To know the adherence to influenza vaccination in elderly people who attended specific workshops. Design: Quasi-experimental study. Location: Primary Care Teams. Participants: 76 people who participated in workshops on influenza, and 116 who did not participate in these workshops used as controls. Main measurements: We compared vaccination percentages between 2009 and 2013, according to data from computerized medical records. A survival analysis was carried out to know how long the patients maintained their vaccination adherence, considering as "non adherence" the first time they were not vaccinated. Results: The proportion of vaccinated patients was higher in those who had participated in the workshops: 68.6 % (95% CI: 54.9-82.3) vs 61.2 % (95% CI: 51.9-70.5), than in those who had not participated, but the differences were not statistically significant (NS). The vaccination was discontinued in 45.1 % (95% CI: 30.5-59.7) and in 42.2 % (95% CI: 32.8-51.7), respectively, with a mean adherence of 2 years in both groups (NS). We found significant differences between both groups in relation to those unvaccinated the year prior to their inclusion in the study who did vaccinate the year after: 14.9 % vs. 5 %, respectively in those who had participated in the workshops and in those who had not participated (p < 0.05). Conclusion: Even though older people's participation in specific workshops on influenza can stimulate influenza vaccination initially, there is no significant long-term improvement

Seguimiento a dos años de pacientes con diabetes mellitus tipo 2 atendidos en dos centros de salud, en España y Portugal / Two-year follow-up of type 2 diabetic patients seen in two health care centers in Spain and Portugal

Objetivo: Conocer los cambios en el grado de control después de 2 años, de pacientes con diabetes mellitus tipo 2 (DM2) en un centro de Salud español (público, SESCAM) y otro portugués (Unidad de Salud Funcional). Diseño: Estudio de cohorte. Emplazamiento: Atención Primaria. Participantes: Pacientes con DM2 que revisados 2 años después de un primer control (julio y noviembre del 2014, respectivamente en Portugal y España). Mediciones Principales: A partir de las historias clínicas informatizas se obtuvieron los siguientes datos: sexo, edad, años de evolución, índice de masa corporal (IMC), microalbuminuria, hemoglobina glicosilada (HbA1c), perfil lipídico, presencia de complicaciones y tratamiento. La información fue introducida en una base de datos informatizada por medio del programa estadístico SPSS 17.0. Se realizó estadística descriptiva y comparación de proporciones y medias/medianas. Resultados: En 2014 se estudiaron 200 pacientes portugueses y 278 españoles. Dos años después, se disponía de información en sus historias clínicas para 135 portugueses y 248 españoles. La media de edad de estos pacientes en 2016 era de 71,2 años (DE: 11,0), con 46,0 % de mujeres. No había diferencias en la distribución por edad y sexo entre ambos centros. La mediana de variación en la HbA1c a los 2 años era 0,0 (rango intercuartil:-0,4 a 0,5), sin diferencias estadísticamente significativas en los portugueses y un moderado aumento (p=0,05) para los españoles. Los portugueses presentaban una disminución media del IMC de 0,05 (IC95 %:-0,27 a 0,37) y los españoles tenían un aumento medio de 0,07 (IC95 %:-0,27 a 0,41), sin existir diferencias estadísticamente significativas. Conclusiones: A los 2 años de seguimiento, los pacientes portugueses mostraron una leve reducción de peso, con estabilidad en sus cifras de HbA1c, mientras que los españoles empeoraron ligeramente en ambos parámetros

Objective: The aim of the study is to know the changes in the degree of control of patients with type 2 diabetes mellitus in a Spanish health center (public, SESCAM) and a Portuguese health center (Functional Health Unit) after a two-year follow-up period. Design: Cohort study. Location: Primary Care. Participants: Patients with type 2 diabetes who were reviewed two years after a first control (July and November 2014, respectively in Portugal and Spain). Main measurements: The data obtained from the computerized clinical records were sex, age, years of disease course, body mass index (BMI), microalbuminuria, glycosylated hemoglobin (HbA1c), lipid profile, complications, and treatment. The information was entered into a computerized database with the statistical program SPSS 17.0. Descriptive statistics and comparison of proportions and means/medians were performed. Results: 200 Portuguese patients and 278 Spanish patients were studied in 2014. Information on their clinical follow-up was available two years after for 135 Portuguese and 248 Spanish. The mean age of these patients in 2016 was 71.2 years (SD: 11.0), with 46.0% of women. There were no differences in the distribution by age and sex in both centers. The median of variation in HbA1c after 2 years was 0.0 (interquartile range:-0.4 to 0.5), without statistically significant (NS) differences for Portuguese patients and moderate increase (p=0.05) for Spanish patients. The Portuguese presented a mean BMI decrease of 0.05 (95%CI:-0.27 to 0.37) and Spanish patients had a mean increase of 0.07 (95%CI:-0.27 to 0.41), NS differences. Conclusion: After 2 years of follow-up, Portuguese patients showed a slight weight reduction, with stability in their HbA1c levels, while Spanish patients worsened slightly in both parameters

At what stage in the undergraduate curriculum is it best to train in family medicine? A study from two medical schools in Spain.

BACKGROUND: A course in family medicine (FM) could dispel the possibility of negative stereotyping about this speciality, and instil in students a greater interest. However, when is it preferable: at the beginning or at the end of undergraduate training? OBJECTIVES: To determine changes in knowledge and attitudes towards FM by medical students completing a course in primary care at the beginning or the end of the undergraduate training and whether those changes anticipate the choice of speciality. METHODS: Students from Albacete and Seville medical schools (primary care course in second and sixth years, respectively) were asked to respond to the 'valuation of attitudes towards and knowledge of family medicine questionnaire' (CAMF). Students from Albacete answered before and after the course, and in Seville second-year students answered at the end of the first trimester. All students were invited to respond again at the end of their undergraduate training. Afterwards, we investigated the score on the speciality exam (order for the election from highest to lowest score) and their choice of speciality. The outcome measures were the MIR exam score, the number in the ranking, the chosen speciality and the result of the CAMF. RESULTS: In Albacete 88 and 64 and in Seville 50 and 98 students responded in their second and sixth years, respectively. In Albacete, mean CAMF scores were 15.4, 22.7 before and after the course, and 21.8 at the end while in Seville, 13.9 in the second year, and 23.5 in the sixth year. Logistic regression analysis showed an association of the choice of FM only with the score on the speciality exam (OR: 0.667; 95%CI: 0.553-0.806). CONCLUSION: There were no significant differences between CAMF scores at the end of undergraduate training. Only the score on the speciality exam predicts FM choice: the higher the score, the lower the probability of choosing FM.

[Risk of pneumococcal disease in elderly patients with and without previous vaccination]. / Riesgo de enfermedad neumocócica en pacientes ancianos con y sin vacunación previa.

OBJECTIVES: To know the pneumococcal vaccination coverage in patients≥65 years old, as well as the risk of pneumococcal disease according to whether or not they received such vaccination. DESIGN: Cross-sectional study, followed by historical cohort. LOCATION: Urban area. PARTICIPANTS: By systematic sampling, 2,805 people≥65 years from the city of Albacete were selected. MAIN MEASUREMENTS: Dependent variable: diagnosis of pneumococcal disease and date. INDEPENDENT VARIABLES: age, sex, chronic pathologies, medication, pneumococcal vaccination and date. The computerized medical records were reviewed, from 1-1-2009 to October-December 2015. A descriptive analysis was carried out, the relative risk of the onset of pneumococcal disease according to vaccination has been calculated, and survival analysis has been carried out, with the statistical program SPSS 17.0. RESULTS: Median age 71 years; 57.2% were women; 46% received polysaccharide vaccine (95% CI 44.1-47.8). Only 10 people received conjugated vaccine. Twenty-two people were diagnosed with invasive pneumococcal disease and 153 non-invasive. The relative risk of pneumococcal disease in vaccinated versus unvaccinated, respectively for invasive and non-invasive, was 1.59 (95% CI 0.69-3.68) and 1.84 (95% CI 1.33-2.54). Cox regression showed a higher risk of non-invasive disease for COPD (1.95; 95% CI 1.32-2.89), smoking (1.87; 95% CI 1.28-2.73), corticoid-therapy (1.73; 95% CI 1.08-2.79), polysaccharide vaccination (141.41; 95% CI 5.92-3,378.49) and age (1.11; 95% CI 1.08-1.14), with interaction between these 2 (0.94, 95% CI 0.91-0.98). CONCLUSIONS: There is an increased risk of pneumococcal disease in patients≥65 years vaccinated with polysaccharide, although with a protective effect in vaccinated older.

Satisfacción de los pacientes atendidos en dos modelos asistenciales de Atención Primaria distintos, en España y Portugal / Satisfaction of patients attended in two different Primary Care models, in Spain and in Portugal

Objetivo: Conocer el grado de satisfacción de los pacientes con la atención recibida en un centro de salud español (público, SESCAM) y otro portugués (Unidad de Salud Funcional). Diseño: Estudio transversal. Emplazamiento: Atención Primaria. Participantes: Pacientes que acudían de forma consecutiva a consulta durante los meses de julio (Portugal) y noviembre (España) de 2014 (80 y 87 pacientes, respectivamente) y 2016 (144 y 174, respectivamente). Mediciones Principales: Cuestionario EUROPEP, con 23 ítems, validado y estandarizado internacionalmente; otras variables: edad, sexo, nivel de estudios. El análisis estadístico incluyó descripción de variables y comparación de respuestas en ambos centros (U de Mann-Whitney). Resultados: En 2014, la media de edad fue de 50,1 años en los españoles y 56,9 en los portugueses (p=0,011); en 2016 no se encontraron diferencias estadísticamente significativas por edad, con una media global de 49,9 años. En ambos años existía un ligero predominio femenino en los dos centros. En general, los pacientes portugueses tenían una opinión más favorable acerca de la atención que recibían. Las diferencias más llamativas (p<0,001) se encontraron, en 2014, para los ítems: el médico le habla suficientemente acerca de sus síntomas (97,2 vs 81,7 %), le ayuda a manejar las emociones (94,5 vs 74,1 %) y con el tiempo de espera (74,7 vs 40,0 %). En 2016: el médico muestra interés sobre su situación (59,9 vs 75,5 %), facilita poder contar sus problemas (59,6 vs 79,0 %), se esmera en el abordaje de sus problemas (55,9 vs 73,3 %), le explora (58,1 vs 81,2 %), le ofrece prevención (50,0 vs 74,5 %), le habla suficientemente acerca de sus síntomas (58,0 vs 77,2 %), le ayuda a manejar las emociones (47,5 vs 71,2 %), sabe lo que se ha hecho durante anteriores visitas (52,8 vs 74,8 %), y con el tiempo de espera (12,9 vs 35,7 %). Con relación a ítems que valoran algunos aspectos relacionados con profesionalismo (escucha, confidencialidad, ayudar a sentirse bien) o administrativos (conseguir una cita o contactar por teléfono), no existían diferencias significativas. Conclusiones: Los pacientes portugueses atendidos en la Unidad de Salud Funcional han mostrado una mayor satisfacción con la asistencia recibida que los atendidos en el centro de salud español

Objective: The aim of the study is to know the level of patient satisfaction with the care received in a Spanish health center (public, SESCAM) and in a Portuguese health center (Functional Health Unit). Design: cross-sectional study. Location: Primary Care. Participants: Patients who visited the health center consecutively during the months of July (Portugal) and November (Spain) in 2014 (80 and 87 patients, respectively) and 2016 (144 and 174, respectively). Main measurements: EUROPEP questionnaire, with 23 items, validated and internationally standardized. Other variables: age, sex, education level. The statistical analysis included a description of the variables and a comparison of answers in both health centers (Mann-Whitney U test). Results: In 2014, the mean age was 50.1 in Spain and 56.9 years in Portugal (p=0.011); in 2016 there were no statistically significant differences (NS) by age, with a global average of 49.9 years. In both years there was a slight female predominance in both centers. In general, Portuguese patients had a more favorable opinion about the care received. The most striking differences (p<0.001) were found, in 2014, for items: the doctor explains sufficiently about their symptoms (97.2 vs 81.7 %), helps to deal with emotions (94.5 vs 74.1 %); and waiting time (74.7 vs 40.0 %). In 2016: the doctor shows interest in their situation (59.9 vs 75.5 %), makes it easier to talk about their problems (59.6 vs 79.0 %), takes great care in addressing their problems (55.9 vs 73.3 %), examines (58.1 vs 81.2 %), provides prevention (50.0 vs 74.5 %), explains sufficiently about their symptoms (58.0 vs 77.2 %), helps to deal with emotions (47.5 vs 71.2 %), knows what has been done during previous visits (52.8 vs 74.8 %), and waiting time (12.9 vs 35.7 %). With regard to questions assessing some aspects related to professionalism (listening skills, confidentiality, helping to feel well) and administrative aspects (getting an appointment, or contact by telephone) there were NS. Conclusion: Portuguese users of Functional Health Unit have shown a higher degree of satisfaction with the care provided compared with those who were attended in the Spanish health center

Frequency and characteristics of Internet use by Spanish teenagers. A cross-sectional study.

INTRODUCTION: Internet has completely changed communication among people in today's world, especially among young users. The objective of this study is to establish the frequency of Internet use by teenagers, and most used apps. POPULATION AND METHODS: This was a crosssectional study. In November 2013, students attending two mandatory secondary schools in Albacete were invited to complete a self-administered questionnaire with close-ended and open questions. Questionnaires were completed in the classroom, either "online" or "with pen and paper". Answers were entered in a computer database using the SPSS 17.0 software. Statistical analysis included a comparison of proportions (χ² test) and mean/median values (Student's t test/non-parametric tests). RESULTS: Nine hundred and sixty-seven students participated; their mean age was 13.8 years old (range: 11-20); 53.5% were girls. Most students (70.9%) lived in the city. Most belonged to a middle (51.3%) and high (34.8%) socioeconomic status. Also most students went online on a daily basis (73.4%); only 0.9% indicated that they never did. The most frequently used apps included WhatsApp (77.1%), social networks (70.1%) and music apps (66.6%). Among girls, the most common Internet use was social networks (p= 0.004), WhatsApp (p < 0.0001), Instagram (p < 0.0001) and listening to music (p= 0.004). Boys most commonly used the Internet to browse the web (p < 0.0001), Skype (p=0.001), play (p < 0.0001) andwatchmovies or TV shows (p= 0.035). CONCLUSIONS: Internet takes up a large part of the time in adolescents' lives, especially as a means of communications, being WhatsApp and social networks the most commonly used apps.

INTRODUCCIÓN: Internet ha transformado la comunicación entre las personas en el mundo actual, especialmente en el caso de los más jóvenes. El objetivo de este estudio es determinar la frecuencia de uso de Internet por adolescentes, así como las aplicaciones utilizadas. POBLACIÓN Y MÉTODOS: Se trata de un estudio transversal. En noviembre de 2013, los estudiantes de la escuela secundaria obligatoria de dos institutos de Albacete fueron invitados a responder un cuestionario autoadministrable, con preguntas de respuesta abierta y cerrada. Contestaron en las aulas, "on line" o con "lápiz y papel". Las respuestas fueron introducidas en una base de datos informatizada, con el programa SPSS 17.0. El análisis estadístico ha incluido comparación de proporciones (chi cuadrado) y de medias/medianas (t de Student/pruebas no paramétricas). RESULTADOS: Participaron 967 estudiantes, con media de edad de 13,8 años (rango: 11-20); 53,5% de mujeres. La mayoría (70,9%) vivían en la ciudad. La clase social era mayoritariamente media (51,3%) y alta (34,8%). La mayoría se conectaba a Internet a diario (73,4%); solo 0,9% decía no conectarse nunca. Las aplicaciones más utilizadas eran WhatsApp (77,1%), redes sociales (70,1%) y relacionadas con música (66,6%). Se ha encontrado una mayor frecuencia de utilización por las mujeres de redes sociales (p= 0,004), WhatsApp (p <0,0001), Instagram (p <0,0001) y escuchar música (p= 0,004). Los varones navegaban más (p <0,0001), utilizaban Skype (p= 0,001), jugaban (p <0,0001) y veían películas o series (p= 0,035). CONCLUSIONES: Internet ocupa una gran parte del tiempo de los adolescentes, especialmente como medio de comunicación, y WhatsApp y las redes sociales son las aplicaciones que utilizan con más frecuencia.

Frecuencia y características de uso de Internet por adolescentes espanoles: Un estudio transversal / Frequency and characteristics of Internet use by Spanish teenagers: A cross-sectional study

Introducción: Internet ha transformado la comunicación entre las personas en el mundo actual, especialmente en el caso de los más jóvenes. El objetivo de este estudio es determinar la frecuencia de uso de Internet por adolescentes, así como las aplicaciones utilizadas. Población y métodos: Se trata de un estudio transversal. En noviembre de 2013, los estudiantes de la escuela secundaria obligatoria de dos institutos de Albacete fueron invitados a responder un cuestionario autoadministrable, con preguntas de respuesta abierta y cerrada. Contestaron en las aulas, "on line" o con "lápiz y papel". Las respuestas fueron introducidas en una base de datos informatizada, con el programa SPSS 17.0. El análisis estadístico ha incluido comparación de proporciones (chi cuadrado) y de medias/medianas (t de Student/pruebas no paramétricas). Resultados: Participaron 967 estudiantes, con media de edad de 13,8 años (rango: 11-20); 53,5% de mujeres. La mayoría (70,9%) vivían en la ciudad. La clase social era mayoritariamente media (51,3%) y alta (34,8%). La mayoría se conectaba a Internet a diario (73,4%); solo 0,9% decía no conectarse nunca. Las aplicaciones más utilizadas eran WhatsApp (77,1%), redes sociales (70,1%) y relacionadas con música (66,6%). Se ha encontrado una mayor frecuencia de utilización por las mujeres de redes sociales (p= 0,004), WhatsApp (p <0,0001), Instagram (p <0,0001) y escuchar música (p= 0,004). Los varones navegaban más (p <0,0001), utilizaban Skype (p= 0,001), jugaban (p <0,0001) y veían películas o series (p= 0,035). Conclusiones: Internet ocupa una gran parte del tiempo de los adolescentes, especialmente como medio de comunicación, y WhatsApp y las redes sociales son las aplicaciones que utilizan con más frecuencia.

Introduction. Internet has completely changed communication among people in today's world, especially among young users. The objective of this study is to establish the frequency of Internet use by teenagers, and most used apps. Population and methods. This was a crosssectional study. In November 2013, students attending two mandatory secondary schools in Albacete were invited to complete a self-administered questionnaire with close-ended and open questions. Questionnaires were completed in the classroom, either "online" or "with pen and paper". Answers were entered in a computer database using the SPSS 17.0 software. Statistical analysis included a comparison of proportions (χ2 test) and mean/median values (Student's t test/non-parametric tests). Results. Nine hundred and sixty-seven students participated; their mean age was 13.8 years old (range: 11-20); 53.5% were girls. Most students (70.9%) lived in the city. Most belonged to a middle (51.3%) and high (34.8%) socioeconomic status. Also most students went online on a daily basis (73.4%); only 0.9% indicated that they never did. The most frequently used apps included WhatsApp (77.1%), social networks (70.1%) and music apps (66.6%). Among girls, the most common Internet use was social networks (p= 0.004), WhatsApp (p < 0.0001), Instagram (p < 0.0001) and listening to music (p= 0.004). Boys most commonly used the Internet to browse the web (p < 0.0001), Skype (p=0.001), play (p < 0.0001) andwatchmovies or TV shows (p= 0.035). Conclusions. Internet takes up a large part of the time in adolescents' lives, especially as a means of communications, being WhatsApp and social networks the most commonly used apps.

Talleres sobre problemas de salud prevalentes con personas integradas en grupos de trabajo en centros de mayores / Workshops on prevalent health issues with people involved in working groups in centres for the elderly

Objetivo: Evaluar cambios en conocimientos de personas mayores que participan en talleres sobre temas de salud. Diseño del estudio: Estudio “antes-después”. Emplazamiento: Comunitario. Participantes: Personas integradas en grupos de trabajo en dos centros de mayores. Intervención: Se programaron intervenciones educativas sobre gripe, osteoporosis y riesgo cardiovascular (RCV). Previo consentimiento informado, los participantes contestaron un cuestionario de conocimientos, datos sociodemográficos y estado general de salud. A continuación se exponía el tema por uno de los miembros del grupo investigador. Se terminaba con un cuestionario postest. Mediciones principales: Variables sociodemográficas, de conocimientos sobre los temas tratados y estado general de salud. Resultados: En el taller sobre gripe participaron 24 personas. Antes del taller 45,8 % conocían los síntomas, 25 % decía que conocía la prevención; después el 58,3 % (NS) y el 70,8 % (p=0,001), respectivamente. En el de osteoporosis participaron 37. Antes del taller, 59,5 % decía conocer algo sobre osteoporosis, y 89,2 % sabían que afecta a los huesos. Conocían la importancia de consumir lácteos 75,7 %. Tras el taller se planteaban cambios: alimentación (13,5 %), ejercicio (18,9 %), visitas a su médico (27 %), varios aspectos (13,5 %). En el de RCV participaron 19. Antes del taller, 57,9 % había oído sobre factores de RCV, aunque 84,2 % no sabía nombrarlos. Tras el taller se redujo en un 50 % las personas que no sabían dar el nombre de algún factor de RCV (p=0,021). Conclusiones: Los conocimientos de las personas participantes en los talleres mejoraban después de los mismos, para los diferentes temas tratados (AU)

Objective: To evaluate changes in knowledge of elderly people who take part in workshops on health issues. Study Design: Before and after study. Participants: People involved in working groups in two centres for the elderly. Procedure: Educational interventions about influenza, osteoporosis, and cardiovascular risk were programmed. Subject to prior informed consent, the participants answered a questionnaire about previous knowledge, sociodemographic data, and overall health. Then, one of the members of the research group explained a subject. To conclude, a post-test questionnaire was completed. Main measurements: Variables related to sociodemographic features, knowledge of the topics discussed, and overall health. Results: 24 people took part in the workshop on influenza. Before the workshop, 45,8% knew the symptoms, 25% said they knew about its prevention. After the workshop, 58,3% (NS) and 70,8% (p=0,001), respectively. Conclusions: People participating in the workshops improved their knowledge of the topics Discussed (AU)

Calidad del sueño según el Pittsburgh Sleep Quality Index en una muestra de pacientes recibiendo cuidados paliativos / Sleep quality according to the pittsburgh sleep quality index in a sample of patients receiving palliative care

Los trastornos del sueño pueden llegar a estar presentes en un 30-96% de los pacientes oncológicos. Tener un sueño de calidad es esencial para conseguir un buen control sintomático al relacionarse las disomnias con otros cuadros clínicos. Objetivos: Conocer la prevalencia de los trastornos del sueño en nuestro programa asistencial de Cuidados Paliativos y valorar la utilidad del cuestionario Pittsburgh Sleep Quality Index (PSQI),como herramienta de estudio de la calidad del sueño, en nuestro ámbito de trabajo. Método: Estudio descriptivo de corte transversal de una muestra obtenida del programa asistencial de la Fundación CUDECA en Málaga. Incluyéndose todos aquellos pacientes que fueron visitados consecutivamente durante un período de 4 meses, descartándose pacientes menores (..) (AU)

Sleep disturbances may occur in between 30-96% of cancer patients. Having a quality sleep is essential to achieve a good control of symptoms, since dysomnias are related to other clinical problems. Objectives: To determine the prevalence of sleep disorders and valuing the usefulness of thePSQI (Pittsburg Sleep quality Index) as a study tool of the quality sleep in our palliative careprogram. Method: A cross-sectional descriptive study was conducted using as a patient sample from our home care program in the CUDECA Foundation in Málaga. We included all those patients in our home care program for a period of 4 months, excluding those patients under the age of (..) (AU)

Cell interactions with hierarchically structured nano-patterned adhesive surfaces.

The activation of well-defined numbers of integrin molecules in predefined areas by adhesion of tissue cells to biofunctionalized micro-nanopatterned surfaces was used to determine the minimum number of activated integrins necessary to stimulate focal adhesion formation. This was realized by combining micellar and conventional e-beam lithography, which enabled deposition of 6 nm large gold nanoparticles on predefined geometries. Patterns with a lateral spacing of 58 nm and a number of gold nanoparticles, ranging from 6 to 3000 per adhesive patch, were used. For α(v) ß(3)-integrin activation, gold nanoparticles were coated with c(-RGDfK-)-thiol peptides, and the remaining glass surface was passivated to prevent non-specific protein adsorption and cell adhesion. Results show that focal adhesion formation is dictated by the underlying hierarchical nanopattern. Adhesive patches with side lengths of 3000 nm and separated by 3000 nm, or with side lengths of 1000 nm and separated by 1000 nm, containing approximately 3007 ± 193 or 335 ± 65 adhesive gold nanoparticles, respectively, induced the formation of actin-associated, paxillin-rich focal adhesions, comparable in size and shape to classical focal adhesions. In contrast, adhesive patches with side lengths of 500, 250 or 100 nm, and separated from adjacent adhesive patches by their respective side lengths, containing 83 ± 11, 30 ± 4, or 6 ± 1 adhesive gold nanoparticles, respectively, showed a significant increase in paxillin domain length, caused by bridging the pattern gap through an actin bundle in order to mechanically, synergistically strengthen each single adhesion site. Neither paxillin accumulation nor adhesion formation was induced if less than 6 c(-RGDfK-)-thiol functionalised gold nanoparticles per adhesion site were presented to cells.

Cooperativity in adhesion cluster formation during initial cell adhesion.

We have studied the initial phase of cell adhesion as a function of the lateral organization of individual integrin molecules with single-cell force microscopy. Nanostructures, consisting of hexagonally ordered gold dots, were prepared with diblock-copolymer micelle lithography and functionalized with arginine- glycine-aspartate peptides, thus defining integrin position with nanometer resolution. Adhesion strength was characterized with an atomic force microscope and both cell detachment forces and work of detachment showed a reinforcement of adhesion if the distance between integrin molecules was <70 nm. This reinforcement had already occurred at cell-substrate contact times <5 min. We believe our results show quantitatively the relevance of the distance between adjacent integrin binding sites rather than their density. Furthermore, we propose a model describing the cooperative stabilization of early integrin clusters as a function of receptor patterning at the nanoscale.